NPC: OK, same set... How about a mutant plant -- a tree, of course -- with a hard, shell-like outer bark? It can either fly or move incredibly fast...or both! So "Steelbark" the mutant oak has the quickness mutation as well as natural armor.
New roll, and this time we'll come up with a Village and an Adventure Hook:
ADVENTURE HOOK: The village shaman has approached the PCs asking for them to investigate an odd nightly occurrence. It seems the villagers are slowly growing scales over their bodies. (See what I did there?) Each morning when they awake, they find even more of their bodies are covered with this patchy fish-like skin. Is it a new mutation? Perhaps the Cephalopoids are to blame? The PCs are told a medicine man who lives alone in a campsite miles away may have a cure -- or at least an answer.
I'm getting a lot of use and inspiration out of these, so I recommend them for your own gaming table. Heck, keep them behind the screen and toss a few if you're stuck for an interesting plot twist or NPC. Rory's Story Cubes are available all over the place. (I got mine at Walmart for less than $8, in fact.)